Total synthesis of (+)-crocacin D.
نویسندگان
چکیده
[structure: see text] The total synthesis of (+)-crocacin D is described. The convergent asymmetric synthesis relies on the use of a Stille cross-coupling between an (E)-vinyl stannane with an (E)-vinyl iodide to establish the (E,E)-dienamide moiety followed by a mild and efficient copper-catalyzed coupling between (+)-crocacin C and a (Z)-vinyl iodide to establish the challenging (Z)-enamide function.
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عنوان ژورنال:
- The Journal of organic chemistry
دوره 70 6 شماره
صفحات -
تاریخ انتشار 2001